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| RND | DATE | TIME | VENUE/COURT | HOME TEAM | AWAY TEAM | ||||
|---|---|---|---|---|---|---|---|---|---|
| 1 | 11/02/22 (Fri) | 19:45 | Monash University Playing Fields - Pitch 1 | 1 | Waverley Wanderers FC | vs | Boronia SC | 0 | View |
| 11/02/22 (Fri) | 20:00 | Esther Park Reserve - Pitch 1 (Grass) | 0 | Lilydale Montrose United | vs | Shepparton South SC | 7 | View | |
| 11/02/22 (Fri) | 20:30 | Edithvale Recreation Reserve - Pitch 1 | 2 | Chelsea FC | vs | St Kilda SC | 0 | View | |
| 12/02/22 (Sat) | 12:00 | FORFEIT | 0 | Mitchell Rangers SC | vs | FC Eaglehawk | 3 | View | |
| 12/02/22 (Sat) | 13:00 | ABD Stadium Broadmeadows Valley Park - Pitch 3 (S) | 1 | Roxburgh Park United S.C | vs | Keilor Wolves SC | 10 | View | |
| 12/02/22 (Sat) | 13:00 | Darebin International Sports Centre - Pitch 1 (S) | 2 | Thornbury Athletic FC Seniors | vs | Sandringham SC | 6 | View | |
| 12/02/22 (Sat) | 13:00 | Lara Recreation Reserve - Pitch 2 | 4 | Lara United FC | vs | Kings Domain FC | 0 | View | |
| 12/02/22 (Sat) | 14:00 | IYU Recreation Reserve (S) | 3 | Pakenham United FC | vs | Breakwater Eagles Sports Club | 1 | View | |
| 12/02/22 (Sat) | 15:00 | Banyul Warri Reserve - Pitch 3 | 7 | Surf Coast FC | vs | Rosebud SC | 1 | View | |
| 12/02/22 (Sat) | 15:00 | Baxter Park - Pitch 1 | 1 | Baxter SC | vs | Mount Waverley City SC | 2 | View | |
| 12/02/22 (Sat) | 15:00 | Bunyip Recreation Reserve | 3 | Bunyip District SC | vs | Sandown Lions FC | 0 | View | |
| 12/02/22 (Sat) | 15:00 | Civic Reserve - Pitch 1 | 0 | Mount Martha SC | vs | Glen Waverley SC | 3 | View | |
| 12/02/22 (Sat) | 15:00 | Dixon Field Reserve - Pitch A | 10 | Gisborne SC | vs | Doreen United SC | 1 | View | |
| 12/02/22 (Sat) | 15:00 | Epsom Huntly Recreation Reserve - Pitch 5 - (NPL) | 1 | Epsom FC | vs | Mentone SC | 2 | View | |
| 12/02/22 (Sat) | 15:00 | Findon Reserve - Pitch 1 | 4 | Uni Hill Eagles FC | vs | Old Ivanhoe SC | 2 | View | |
| 12/02/22 (Sat) | 15:00 | George Andrews Reserve - Pitch 1 - (NPL) | 0 | Dandenong South S.C | vs | Hampton Park United Sparrows FC | 2 | View | |
| 12/02/22 (Sat) | 15:00 | Greaves Reserve (Alan Carter Pavilion) - Pitch 1 | 4 | White Star Dandenong SC | vs | Old St Kevins SC | 2 | View | |
| 12/02/22 (Sat) | 15:00 | Hillsview Recreation Reserve - Pitch 1 (S) | 2 | Bundoora United F.C | vs | Melbourne City FC | 1 | View | |
| 12/02/22 (Sat) | 15:00 | Jubilee Park (S) - (NPL) | 1 | Albert Park SC | vs | Ringwood City FC | 6 | View | |
| 12/02/22 (Sat) | 15:00 | Prospect Hill Reserve | 2 | Casey Panthers SC | vs | Melton Phoenix FC | 6 | View | |
| 12/02/22 (Sat) | 15:00 | Reema Reserve - Pitch 1 | 5 | Endeavour United SC | vs | Lyndale United FC | 3 | View | |
| 12/02/22 (Sat) | 15:00 | Sumner Park | 1 | Brunswick Zebras FC | vs | Greenvale United SC | 1 | View | |
| 12/02/22 (Sat) | 15:00 | Trekardo Park #1 | 0 | Ballarat S.C | vs | Old Melburnians SC | 1 | View | |
| 12/02/22 (Sat) | 15:00 | Wallace Reserve - Pitch 1 | 2 | Glenroy Lions FC | vs | Spring Gully United SC | 0 | View | |
| 12/02/22 (Sat) | 15:15 | Kingston Heath Soccer Complex - Pitch 2 (S) | 5 | Aspendale SC | vs | Deakin University SC | 0 | View | |
| 12/02/22 (Sat) | 15:30 | Park Avenue Reserve (S) - (NPL) | 1 | Manningham Juventus FC | vs | West Preston SC | 0 | View | |
| 12/02/22 (Sat) | 16:00 | ABD Stadium Broadmeadows Valley Park - Pitch 3 (S) | 2 | Meadow Park SC | vs | Seniors - MBUFC | 0 | View | |
| 12/02/22 (Sat) | 16:00 | Darebin International Sports Centre - Pitch 1 (S) | 3 | North Melbourne Athletic FC | vs | Swinburne FC | 0 | View | |
| 12/02/22 (Sat) | 16:00 | Jack Edwards Reserve - Pitch 2 (S) | 9 | Chisholm United FC | vs | Wyndham FC | 0 | View | |
| 12/02/22 (Sat) | 16:00 | Power Reserve | 0 | FC Noble Hurricanes | vs | West Point Soccer Club | 3 | View | |
| 12/02/22 (Sat) | 16:00 | R.G.C. Cook Recreational Reserve - Pitch 1 | 1 | Maribyrnong Greens SC | vs | Plenty Valley Lions FC | 7 | View | |
| 12/02/22 (Sat) | 16:00 | Veneto Club - David Barro Stadium (S) - (NPL) | 3 | Knox United SC | vs | Barwon SC | 5 | View | |
| 12/02/22 (Sat) | 17:00 | Barton Recreation Reserve | 0 | Barton United FC | vs | Northern Falcons SC | 3 | View | |
| 12/02/22 (Sat) | 17:00 | Esther Park Reserve - Pitch 1 (Grass) | 1 | Croydon City SC | vs | East Kew FC | 2 | View | |
| 12/02/22 (Sat) | 17:00 | Greensborough College - Sporting Precinct (S) | 2 | Watsonia Heights FC | vs | Bendigo City FC | 2 | View | |
| 12/02/22 (Sat) | 19:00 | ABD Stadium Broadmeadows Valley Park - Pitch 3 (S) | 3 | FC Tullamarine | vs | Somerville Eagles Soccer Club | 1 | View | |
| 12/02/22 (Sat) | 19:00 | Arndell Park Reserve - Pitch 3 (S) | 1 | Truganina Hornets SC | vs | Yarra Jets FC | 0 | View | |
| 13/02/22 (Sun) | FORFEIT | 3 | Australia Cup | vs | Seaford United SC | 0 | View | ||
| 13/02/22 (Sun) | FORFEIT | 0 | East Bentleigh SC | vs | Tatura SC | 3 | View | ||
| 13/02/22 (Sun) | FORFEIT | 0 | Maidstone United SC | vs | Moonee Valley Knights FC | 3 | View | ||
| 13/02/22 (Sun) | FORFEIT | 0 | Endeavour Hills Fire SC Cup | vs | Golden Plains SC | 3 | View | ||
| 13/02/22 (Sun) | FORFEIT | 0 | Noble Park SC | vs | Barnstoneworth United Football Club (VIC) | 3 | View | ||
| 13/02/22 (Sun) | FORFEIT | 3 | Mildura City SC | vs | Bell Park SC | 0 | View | ||
| 13/02/22 (Sun) | FORFEIT | 3 | Alphington FC | vs | Old Xaverians SC | 0 | View | ||
| 13/02/22 (Sun) | FORFEIT | 3 | La Trobe University SC | vs | Old Trinity Grammarians SC | 0 | View | ||
| 13/02/22 (Sun) | 11:00 | FORFEIT | 3 | Melbourne University Soccer Club | vs | South East United FC | 0 | View | |
| 13/02/22 (Sun) | 11:00 | FORFEIT | 0 | Keon Park SC | vs | Riversdale SC | 3 | View | |
| 13/02/22 (Sun) | 13:30 | Darebin International Sports Centre - Pitch 1 (S) | 2 | Darebin United SC | vs | Spring Hills FC | 1 | View | |
| 13/02/22 (Sun) | 15:00 | Ross Reserve - Pitch 2 | 8 | Springvale City SC | vs | Warrnambool Wolves | 0 | View | |
| 13/02/22 (Sun) | 16:00 | Waratah Reserve - Pitch 3 | 1 | Keysborough SC | vs | Monash City Villareal FC | 3 | View | |
| 13/02/22 (Sun) | 16:30 | Monash University Playing Fields - Pitch 2 | 1 | Glen Eira FC | vs | Laverton FC | 8 | View | |
| 13/02/22 (Sun) | 17:00 | FORFEIT | 0 | Ocean Grove SC | vs | Balmoral FC | 3 | View | |
| 2 | 18/02/22 (Fri) | 19:00 | ABD Stadium Broadmeadows Valley Park - Pitch 3 (S) | 2 | Meadow Park SC | vs | Northern Falcons SC | 0 | View |
| 18/02/22 (Fri) | 20:30 | Carrum Downs Recreation Reserve | 1 | Frankston Pines SC | vs | Albion Rovers FC | 1 | View | |
| 18/02/22 (Fri) | 20:30 | Lara Recreation Reserve - Pitch 1 | 1 | Lara United FC | vs | Chelsea FC | 1 | View | |
| 19/02/22 (Sat) | 12:00 | Serbian Sports Centre - Pitch 4 | 1 | Noble Park United FC | vs | Upfield SC | 2 | View | |
| 19/02/22 (Sat) | 13:00 | McIvor Reserve - Pitch 1 | 4 | Westvale Olympic FC | vs | Endeavour United SC | 0 | View | |
| 19/02/22 (Sat) | 13:00 | Parkmore Soccer Club | 0 | Brighton SC | vs | Collingwood City FC | 1 | View | |
| 19/02/22 (Sat) | 13:00 | R.G.C. Cook Recreational Reserve - Pitch 1 | 3 | Lalor United Senior FC | vs | Mount Waverley City SC | 0 | View | |
| 19/02/22 (Sat) | 14:00 | Esther Park Reserve - Pitch 2 (Synthetic) | 2 | Mooroolbark SC | vs | Riversdale SC | 2 | View | |
| 19/02/22 (Sat) | 14:00 | Paisley Park - Pitch 2 | 1 | Keilor Wolves SC | vs | Mill Park SC | 0 | View | |
| 19/02/22 (Sat) | 14:30 | Knox Regional Football Centre - Pitch 1 | 1 | Glen Waverley SC | vs | Moonee Valley Knights FC | 4 | View | |
| 19/02/22 (Sat) | 14:30 | Serbian Sports Centre - Pitch 4 | 1 | Old Scotch SC | vs | Plenty Valley Lions FC | 0 | View | |
| 19/02/22 (Sat) | BYE | BYE | Knox City FC | ||||||
| 19/02/22 (Sat) | BYE | BYE | Sunbury United SC | ||||||
| 19/02/22 (Sat) | BYE | BYE | Monbulk Rangers SC | ||||||
| 19/02/22 (Sat) | BYE | BYE | Hume United FC | ||||||
| 19/02/22 (Sat) | BYE | BYE | Skye United FC | ||||||
| 19/02/22 (Sat) | BYE | BYE | Watsonia Heights FC | ||||||
| 19/02/22 (Sat) | BYE | BYE | Hoppers Crossing SC | ||||||
| 19/02/22 (Sat) | BYE | BYE | Altona East Phoenix SC | ||||||
| 19/02/22 (Sat) | BYE | BYE | Ashburton United SC | ||||||
| 19/02/22 (Sat) | BYE | BYE | Williamstown SC | ||||||
| 19/02/22 (Sat) | 15:00 | Anderson Park | 3 | Doncaster Rovers SC | vs | FC Tullamarine | 1 | View | |
| 19/02/22 (Sat) | 15:00 | Bosnia and Herzegovina Centre - Pitch 1 | 2 | Heatherton United SC | vs | Geelong Rangers SC | 1 | View | |
| 19/02/22 (Sat) | 15:00 | Bunyip Recreation Reserve | 1 | Bunyip District SC | vs | Elwood City SC | 4 | View | |
| 19/02/22 (Sat) | 15:00 | Centenary Park - Pitch 1 - (NPL) | 3 | Peninsula Strikers Senior FC | vs | North Melbourne Athletic FC | 1 | View | |
| 19/02/22 (Sat) | 15:00 | Duffy Street Reserve | 2 | Hampton East Brighton FC | vs | Epping City SC | 4 | View | |
| 19/02/22 (Sat) | 15:00 | Findon Reserve - Pitch 1 | 2 | Uni Hill Eagles FC | vs | Australia Cup | 2 | View | |
| 19/02/22 (Sat) | 15:00 | FORFEIT | 3 | Sebastopol Vikings SC | vs | Altona North Soccer Club | 0 | View | |
| 19/02/22 (Sat) | 15:00 | FORFEIT | 0 | Golden Plains SC | vs | Point Cook FC | 3 | View | |
| 19/02/22 (Sat) | 15:00 | Grange Reserve - Pitch 1 [Hoppers Crossing] | 1 | Barnstoneworth United Football Club (VIC) | vs | Heidelberg Eagles SC | 3 | View | |
| 19/02/22 (Sat) | 15:00 | Hillsview Recreation Reserve - Pitch 1 (S) | 2 | Bundoora United F.C | vs | Manningham Juventus F.C | 2 | View | |
| 19/02/22 (Sat) | 15:00 | Howard Glover Reserve | 1 | Barwon SC | vs | Chisholm United FC | 0 | View | |
| 19/02/22 (Sat) | 15:00 | IYU Recreation Reserve (S) | 1 | Pakenham United FC | vs | White Star Dandenong SC | 1 | View | |
| 19/02/22 (Sat) | 15:00 | Jack Thomas Reserve - Pitch 1 - (NPL) | 5 | Berwick City SC | vs | Middle Park F.C | 0 | View | |
| 19/02/22 (Sat) | 15:00 | Jubilee Park (S) - (NPL) | 2 | Ringwood City FC | vs | Monash City Villarreal FC | 4 | View | |
| 19/02/22 (Sat) | 15:00 | KM Reedy Reserve - Pitch 1 | 2 | Western Suburbs SC | vs | Hampton Park United Sparrows FC | 3 | View | |
| 19/02/22 (Sat) | 15:00 | La Trobe University Lower Playing Fields Academy Pitch | 2 | Brandon Park SC | vs | La Trobe University SC | 0 | View | |
| 19/02/22 (Sat) | 15:00 | Laverton Park Reserve - Pitch 1 | 1 | Laverton FC | vs | Whitehorse United SC | 2 | View | |
| 19/02/22 (Sat) | 15:00 | Monash University Playing Fields - Pitch 1 | 2 | Monash University SC | vs | Truganina Hornets SC | 0 | View | |
| 19/02/22 (Sat) | 15:00 | Monash University Playing Fields - Pitch 2 | 0 | Old Melburnians SC | vs | Craigieburn City FC | 2 | View | |
| 19/02/22 (Sat) | 15:00 | Power Reserve | 2 | Rowville Eagles SC | vs | Melbourne University Soccer Club | 0 | View | |
| 19/02/22 (Sat) | 15:00 | R.G.C. Cook Recreational Reserve - Pitch 2 | 2 | Diamond Valley United SC | vs | Tatura SC | 0 | View | |
| 19/02/22 (Sat) | 15:00 | Sumner Park | 0 | Brunswick Zebras FC | vs | West Point Soccer Club | 1 | View | |
| 19/02/22 (Sat) | 15:00 | Wallace Reserve - Pitch 1 | 1 | Glenroy Lions FC | vs | Balmoral FC | 0 | View | |
| 19/02/22 (Sat) | 15:00 | Waratah Reserve - Pitch 1 - (NPL) | 0 | Mentone SC | vs | Moreland United SC | 4 | View | |
| 19/02/22 (Sat) | 15:15 | Greensborough College - Sporting Precinct (S) | 0 | South Yarra SC | vs | Shepparton South SC | 0 | View | |
| 19/02/22 (Sat) | 16:00 | Edithvale Recreation Reserve - Pitch 1 | 3 | Aspendale SC | vs | Surf Coast FC | 4 | View | |
| 19/02/22 (Sat) | 16:00 | MacPherson Park - Pitch 1 | 1 | Melton Phoenix FC | vs | Gisborne SC | 0 | View | |
| 19/02/22 (Sat) | 16:00 | Tatterson Park - Pitch 1 | 2 | Sandringham SC | vs | Springvale City SC | 0 | View | |
| 19/02/22 (Sat) | 16:00 | Veneto Club - David Barro Stadium (S) - (NPL) | 7 | Moonee Ponds United SC | vs | Alphington FC | 3 | View | |
| 19/02/22 (Sat) | 17:00 | Esther Park Reserve - Pitch 1 (Grass) | 2 | East Kew FC | vs | Bayside Argonauts FC | 3 | View | |
| 19/02/22 (Sat) | 19:00 | Truscott Reserve No. 1 | 1 | FC Eaglehawk | vs | Fawkner SC | 4 | View | |
| 20/02/22 (Sun) | 14:00 | Aero Ovals - Pitch 1 | 1 | Mildura City SC | vs | Waverley Wanderers FC | 1 | View | |
| 20/02/22 (Sun) | 15:00 | Paisley Park - Pitch 3 | 5 | Westgate FC | vs | Darebin United SC | 3 | View | |
| 20/02/22 (Sun) | 17:00 | Polish Sports & Recreation Complex - Pitch 1 | 2 | North Caulfield Senior FC | vs | Western Eagles SC | 3 | View | |
| 3 | 04/03/22 (Fri) | 19:30 | Churchill Reserve - Pitch 1 - (NPL) | 1 | Brandon Park SC | vs | FC Strathmore | 2 | View |
| 04/03/22 (Fri) | 20:00 | Carrum Downs Recreation Reserve | 6 | Frankston Pines SC | vs | Lara United FC | 0 | View | |
| 04/03/22 (Fri) | 20:00 | Esther Park Reserve - Pitch 1 (Grass) | 2 | Whitehorse United SC | vs | Hume United FC | 1 | View | |
| 04/03/22 (Fri) | 20:00 | Paisley Park - Pitch 1 - (NPL) | 0 | Westgate FC | vs | Keilor Wolves SC | 1 | View | |
| 05/03/22 (Sat) | 12:30 | Monash University Playing Fields - Pitch 2 | 0 | Malvern City FC | vs | Old Scotch SC | 2 | View | |
| 05/03/22 (Sat) | 13:00 | R.G.C. Cook Recreational Reserve - Pitch 1 | 1 | Lalor United Senior FC | vs | Williamstown SC | 2 | View | |
| 05/03/22 (Sat) | 14:00 | Myers Reserve - Pitch 1 | 4 | Corio SC | vs | Warragul United SC | 2 | View | |
| 05/03/22 (Sat) | 14:00 | Tatterson Park - Pitch 1 | 11 | South Springvale FC | vs | Hampton Park United Sparrows FC | 0 | View | |
| 05/03/22 (Sat) | BYE | BYE | Beaumaris SC | ||||||
| 05/03/22 (Sat) | 15:00 | Aston Fields - Pitch 1 | 0 | Craigieburn City FC | vs | Melton Phoenix FC | 0 | View | |
| 05/03/22 (Sat) | 15:00 | Bosnia and Herzegovina Centre - Pitch 1 | 0 | Heatherton United SC | vs | Sunbury United SC | 0 | View | |
| 05/03/22 (Sat) | 15:00 | Centenary Park - Pitch 2 | 1 | Peninsula Strikers Senior FC | vs | Eltham Redbacks FC | 3 | View | |
| 05/03/22 (Sat) | 15:00 | Dallas Brooks Park - Pitch 1 - (NPL) | 6 | Mornington SC | vs | Uni Hill Eagles FC | 0 | View | |
| 05/03/22 (Sat) | 15:00 | Dorothy Laver West Reserve - (NPL) | 4 | Ashburton United SC | vs | Monash City Villareal FC | 1 | View | |
| 05/03/22 (Sat) | 15:00 | East Keilor Leisure Centre - Pitch 1 (S) | 2 | Moonee Valley Knights FC | vs | Epping City SC | 4 | View | |
| 05/03/22 (Sat) | 15:00 | FORFEIT | 3 | Casey Comets FC | vs | Fawkner SC | 0 | View | |
| 05/03/22 (Sat) | 15:00 | FORFEIT | 3 | Altona City SC | vs | Surf Coast FC | 0 | View | |
| 05/03/22 (Sat) | 15:00 | Gilwell Park (Mosaic Reserve) - Pitch 1 | 1 | Whittlesea United SC | vs | Doncaster Rovers SC | 1 | View | |
| 05/03/22 (Sat) | 15:00 | Gladstone Park Reserve - Pitch 1 | 1 | Meadow Park SC | vs | Keilor Park SC | 4 | View | |
| 05/03/22 (Sat) | 15:00 | Grange Reserve - Pitch 1 [Hoppers Crossing] | 4 | Collingwood City FC | vs | Hoppers Crossing SC | 1 | View | |
| 05/03/22 (Sat) | 15:00 | Greensborough College - Sporting Precinct (S) | 3 | Watsonia Heights FC | vs | Bayside Argonauts FC | 2 | View | |
| 05/03/22 (Sat) | 15:00 | Jack Thomas Reserve - Pitch 1 - (NPL) | 2 | Berwick City SC | vs | Altona East Phoenix SC | 2 | View | |
| 05/03/22 (Sat) | 15:00 | Keilor Lodge Reserve - Pitch 1 | 6 | Sydenham Park SC | vs | Western Eagles SC | 1 | View | |
| 05/03/22 (Sat) | 15:00 | Lawton Park - Pitch 1 | 0 | Skye United FC | vs | Banyule City SC | 4 | View | |
| 05/03/22 (Sat) | 15:00 | McKechnie Reserve - Pitch 1 | 3 | Westvale Olympic FC | vs | Knox City FC | 1 | View | |
| 05/03/22 (Sat) | 15:00 | Monbulk Regional Soccer Facility - Pitch 1 (S) | 0 | Monbulk Rangers SC | vs | Elwood City SC | 4 | View | |
| 05/03/22 (Sat) | 15:00 | Quarries Park | 5 | FC Clifton Hill | vs | Rowville Eagles SC | 2 | View | |
| 05/03/22 (Sat) | 15:00 | Serbian Sports Centre - Pitch 4 | 0 | Greater Dandenong FC | vs | West Point Soccer Club | 1 | View | |
| 05/03/22 (Sat) | 15:00 | St Georges #1 | 6 | Sebastopol Vikings SC | vs | Barwon SC | 2 | View | |
| 05/03/22 (Sat) | 15:00 | Wallace Reserve - Pitch 1 | 2 | Glenroy Lions FC | vs | White Star Dandenong SC | 4 | View | |
| 05/03/22 (Sat) | 15:15 | Paisley Park - Pitch 3 | 1 | Yarraville FC | vs | Heidelberg Eagles SC | 0 | View | |
| 05/03/22 (Sat) | 15:30 | Park Avenue Reserve (S) - (NPL) | 3 | Manningham Juventus F.C | vs | Moreland United SC | 1 | View | |
| 05/03/22 (Sat) | 16:00 | Gibb Reserve - Pitch 1 | 5 | Upfield SC | vs | Point Cook FC | 1 | View | |
| 05/03/22 (Sat) | 17:00 | Bastow 1 | 3 | Fitzroy City SC | vs | South Yarra SC | 0 | View | |
| 05/03/22 (Sat) | 17:00 | Monash University Playing Fields - Pitch 1 | 2 | Monash University SC | vs | Riversdale SC | 0 | View | |
| 05/03/22 (Sat) | 17:00 | Veneto Club - David Barro Stadium (S) - (NPL) | 1 | Moonee Ponds United SC | vs | Bentleigh United Cobras FC | 1 | View | |
| 05/03/22 (Sat) | 17:30 | City Vista Pavilion & Sports Field - Pitch 1 | 1 | Caroline Springs George Cross FC | vs | Essendon Royals SC | 2 | View | |
| 06/03/22 (Sun) | 15:00 | Monash University Playing Fields - Pitch 3 | 7 | Mazenod Football Club | vs | Mildura City SC | 3 | View | |
| 07/03/22 (Mon) | 20:00 | Veneto Club - David Barro Stadium (S) - (NPL) | 1 | Boroondara-Carey Eagles | vs | Diamond Valley United SC | 0 | View | |
| 11/03/22 (Fri) | 20:00 | Monash University Playing Fields - Pitch 2 | 1 | Sandringham SC | vs | Brimbank Stallions FC | 3 | View | |
| 4 | 22/03/22 (Tue) | 19:30 | Ballarat Regional Soccer Facility - Pitch 1 | 3 | Ballarat City FC | vs | South Springvale FC | 0 | View |
| 22/03/22 (Tue) | 19:30 | Kingston Heath Soccer Complex - Pitch 1 - (NPL) | 4 | Bentleigh Greens SC | vs | Werribee City FC | 1 | View | |
| 22/03/22 (Tue) | 19:30 | Stead Park - Pitch 1 - (NPL) | 0 | Geelong SC | vs | Heidelberg United FC | 4 | View | |
| 22/03/22 (Tue) | 19:30 | The Grange Reserve - (NPL) | 0 | Pascoe Vale FC | vs | Kingston City FC | 1 | View | |
| 22/03/22 (Tue) | 19:45 | FORFEIT | 3 | Goulburn Valley Suns FC | vs | Casey Comets FC | 0 | View | |
| 22/03/22 (Tue) | 20:00 | Churchill Reserve - Pitch 1 - (NPL) | 7 | St Albans Saints SC | vs | Melton Phoenix FC | 1 | View | |
| 22/03/22 (Tue) | 20:00 | Greaves Reserve (Alan Carter Pavilion) - Pitch 1 | 5 | White Star Dandenong SC | vs | Monash University SC | 1 | View | |
| 22/03/22 (Tue) | 20:30 | Veneto Club - David Barro Stadium (S) - (NPL) | 2 | Boroondara-Carey Eagles | vs | Melbourne Knights FC | 3 | View | |
| 23/03/22 (Wed) | BYE | BYE | Watsonia Heights FC | ||||||
| 23/03/22 (Wed) | BYE | BYE | FC Bulleen Lions | ||||||
| 23/03/22 (Wed) | BYE | BYE | Elwood City SC | ||||||
| 23/03/22 (Wed) | BYE | BYE | Dandenong City SC | ||||||
| 23/03/22 (Wed) | BYE | BYE | Fitzroy City SC | ||||||
| 23/03/22 (Wed) | 19:30 | John Cain Memorial Park - Pitch 1 | 1 | Northcote City FC | vs | Yarraville FC | 1 | View | |
| 23/03/22 (Wed) | 19:30 | Kevin Bartlett Reserve - Fletcher 1 | 0 | Old Scotch SC | vs | Collingwood City FC | 4 | View | |
| 23/03/22 (Wed) | 19:30 | Paisley Park - Pitch 1 - (NPL) | 9 | Altona Magic SC | vs | Bentleigh United Cobras FC | 1 | View | |
| 23/03/22 (Wed) | 20:00 | Elcho Park - Pitch 2 | 4 | Moreland City FC | vs | North Geelong Warriors FC | 1 | View | |
| 23/03/22 (Wed) | 20:00 | Epping Stadium - (NPL) | 1 | Whittlesea Ranges FC | vs | Sebastopol Vikings SC | 1 | View | |
| 23/03/22 (Wed) | 20:00 | Gibb Reserve - Pitch 1 | 3 | Upfield SC | vs | Sydenham Park SC | 0 | View | |
| 29/03/22 (Tue) | 19:00 | Wembley Park - (NPL) | 2 | Box Hill United FC | vs | Ashburton United SC | 0 | View | |
| 29/03/22 (Tue) | 19:15 | Egan Lee Reserve - Pitch 1 | 2 | Eastern Lions SC | vs | Brimbank Stallions FC | 3 | View | |
| 29/03/22 (Tue) | 19:30 | Cross Keys Reserve - Pitch 1 - (NPL) | 2 | Essendon Royals SC | vs | Brunswick Juventus FC | 0 | View | |
| 29/03/22 (Tue) | 19:30 | JL Murphy Reserve - SS Anderson Oval - Pitch 1 - (NPL) | 0 | Mazenod Football Club | vs | Port Melbourne Sharks SC | 3 | View | |
| 29/03/22 (Tue) | 19:30 | JT Gray Reserve - Pitch 1 | 1 | Williamstown SC | vs | Whittlesea United SC | 1 | View | |
| 29/03/22 (Tue) | 19:30 | Larissa Reserve | 5 | North Sunshine Eagles F.C. | vs | Manningham Juventus F.C | 0 | View | |
| 29/03/22 (Tue) | 19:30 | Paisley Park - Pitch 1 - (NPL) | 1 | Altona East Phoenix SC | vs | Mornington SC | 0 | View | |
| 29/03/22 (Tue) | 19:45 | Eltham North Reserve - Pitch 1 (S) - (NPL) | 3 | Eltham Redbacks FC | vs | Corio SC | 1 | View | |
| 29/03/22 (Tue) | 19:45 | Jack Edwards Reserve - (NPL) | 4 | Oakleigh Cannons FC | vs | Epping City SC | 0 | View | |
| 29/03/22 (Tue) | 20:00 | Carrum Downs Recreation Reserve | 2 | Frankston Pines SC | vs | FC Clifton Hill | 2 | View | |
| 29/03/22 (Tue) | 20:00 | Lawton Park - Pitch 1 | 1 | Langwarrin SC | vs | Hume City FC | 1 | View | |
| 30/03/22 (Wed) | 19:00 | Tom Roberts Reserve - Pitch 1 | 1 | West Point Soccer Club | vs | Whitehorse United SC | 4 | View | |
| 30/03/22 (Wed) | 19:30 | Bosnia and Herzegovina Centre - Pitch 1 | 2 | Banyule City SC | vs | Heatherton United SC | 1 | View | |
| 30/03/22 (Wed) | 19:30 | George Andrews Reserve - Pitch 1 - (NPL) | 6 | Dandenong Thunder FC | vs | Brunswick City SC | 1 | View | |
| 30/03/22 (Wed) | 19:30 | Hume City Stadium - Pitch 1 (NPL) | 4 | Avondale FC | vs | South Melbourne FC | 1 | View | |
| 30/03/22 (Wed) | 19:45 | Esther Park Reserve - Pitch 2 (Synthetic) | 5 | Manningham United Blues FC | vs | Keilor Park SC | 0 | View | |
| 30/03/22 (Wed) | 19:45 | FORFEIT | 3 | Doveton SC | vs | FC Strathmore | 0 | View | |
| 30/03/22 (Wed) | 20:00 | Green Gully Reserve - Pitch 4 | 3 | Keilor Wolves SC | vs | Westvale Olympic FC | 2 | View | |
| 30/03/22 (Wed) | 20:00 | Serbian Sports Centre - Pitch 1 - (NPL) | 4 | Springvale White Eagles FC | vs | Altona City SC | 0 | View | |
| 05/04/22 (Tue) | 20:00 | Green Gully Reserve - Pitch 1 - (NPL) | 6 | Green Gully SC | vs | Nunawading City FC | 0 | View | |
| 06/04/22 (Wed) | 19:30 | The Grange Reserve - (NPL) | 4 | Beaumaris SC | vs | Preston Lions FC | 3 | View | |
| 5 | 13/04/22 (Wed) | 19:30 | Jack Edwards Reserve - (NPL) | 12 | Oakleigh Cannons FC | vs | White Star Dandenong SC | 0 | View |
| 19/04/22 (Tue) | 19:30 | Cross Keys Reserve - Pitch 1 - (NPL) | 4 | Essendon Royals SC | vs | Eltham Redbacks FC | 2 | View | |
| 19/04/22 (Tue) | 19:30 | Paisley Park - Pitch 1 - (NPL) | 5 | Heidelberg United FC | vs | Altona East Phoenix SC | 0 | View | |
| 20/04/22 (Wed) | 19:00 | Greensborough College - Sporting Precinct (S) | 5 | Moreland City FC | vs | Watsonia Heights FC | 1 | View | |
| 20/04/22 (Wed) | 19:30 | Ballarat Regional Soccer Facility - Pitch 1 | 4 | Ballarat City FC | vs | Springvale White Eagles FC | 1 | View | |
| 20/04/22 (Wed) | 19:30 | Esther Park Reserve - Pitch 2 (Synthetic) | 5 | Doveton SC | vs | Whitehorse United SC | 2 | View | |
| 20/04/22 (Wed) | 19:30 | Kingston Heath Soccer Complex - Pitch 1 | 2 | Bentleigh Greens SC | vs | Altona Magic SC | 1 | View | |
| 20/04/22 (Wed) | 19:30 | Knights Stadium - Pitch 1 - (NPL) | 2 | Melbourne Knights FC | vs | FC Bulleen Lions | 0 | View | |
| 20/04/22 (Wed) | 19:30 | The Grange Reserve - (NPL) | 2 | Kingston City FC | vs | Avondale FC | 2 | View | |
| 26/04/22 (Tue) | 19:00 | Beaumaris Secondary College | 1 | Beaumaris SC | vs | Upfield SC | 1 | View | |
| 26/04/22 (Tue) | 19:00 | Wembley Park - (NPL) | 2 | Box Hill United FC | vs | Banyule City SC | 3 | View | |
| 26/04/22 (Tue) | 19:30 | Hume City Stadium - Pitch 1 (NPL) | 1 | Hume City FC | vs | Dandenong City SC | 0 | View | |
| 26/04/22 (Tue) | 19:30 | JL Murphy Reserve - SS Anderson Oval - Pitch 1 - (NPL) | 4 | Port Melbourne Sharks SC | vs | Manningham United Blues FC | 0 | View | |
| 26/04/22 (Tue) | 19:30 | John McEwen Reserve - Pitch 1 | 5 | Goulburn Valley Suns FC | vs | North Sunshine Eagles F.C. | 0 | View | |
| 26/04/22 (Tue) | 19:30 | Kevin Bartlett Reserve - Bastow 1 | 0 | Fitzroy City SC | vs | Green Gully SC | 3 | View | |
| 26/04/22 (Tue) | 19:30 | Knights Stadium - Pitch 1 - (NPL) | 2 | Brimbank Stallions FC | vs | Yarraville FC | 1 | View | |
| 26/04/22 (Tue) | 19:45 | Elwood Park (Esplanade Oval) | 1 | Elwood City SC | vs | Collingwood City FC | 5 | View | |
| 26/04/22 (Tue) | 19:45 | George Andrews Reserve - Pitch 1 - (NPL) | 1 | FC Clifton Hill | vs | Dandenong Thunder FC | 3 | View | |
| 27/04/22 (Wed) | 20:00 | Churchill Reserve - Pitch 1 - (NPL) | 4 | St Albans Saints SC | vs | Whittlesea Ranges FC | 2 | View | |
| 27/04/22 (Wed) | 20:00 | Green Gully Reserve 4 | 1 | Keilor Wolves SC | vs | Whittlesea United SC | 1 | View | |
| 6 | 10/05/22 (Tue) | 19:00 | Cross Keys Reserve - Pitch 1 - (NPL) | 2 | Essendon Royals SC | vs | Avondale FC | 4 | View |
| 10/05/22 (Tue) | 19:30 | George Andrews Reserve - Pitch 1 - (NPL) | 0 | Doveton SC | vs | Green Gully SC | 4 | View | |
| 10/05/22 (Tue) | 19:30 | Jack Edwards Reserve - (NPL) | 1 | Oakleigh Cannons FC | vs | Hume City FC | 0 | View | |
| 10/05/22 (Tue) | 19:30 | The Grange Reserve - (NPL) | 3 | Heidelberg United FC | vs | Ballarat City FC | 1 | View | |
| 11/05/22 (Wed) | 19:30 | City Vista Pavilion & Sports Field - Pitch 1 | 3 | Brimbank Stallions FC | vs | Moreland City FC | 0 | View | |
| 11/05/22 (Wed) | 19:30 | Hume City Stadium - Pitch 1 (NPL) | 2 | Banyule City SC | vs | Goulburn Valley Suns FC | 1 | View | |
| 17/05/22 (Tue) | 19:30 | George Andrews Reserve - Pitch 1 - (NPL) | 1 | Dandenong Thunder FC | vs | Port Melbourne Sharks SC | 0 | View | |
| 17/05/22 (Tue) | 19:30 | Knights Stadium - Pitch 1 - (NPL) | 1 | Melbourne Knights FC | vs | Collingwood City FC | 0 | View | |
| 18/05/22 (Wed) | 19:00 | Gilwell Park (Mosaic Reserve) - Pitch 1 | 4 | Whittlesea United SC | vs | Upfield SC | 0 | View | |
| 18/05/22 (Wed) | 19:30 | Kingston Heath Soccer Complex - Pitch 1 | 3 | Bentleigh Greens SC | vs | St Albans Saints SC | 0 | View | |
| 7 | 07/06/22 (Tue) | 19:30 | Knights Stadium - Pitch 1 - (NPL) | 0 | Melbourne Knights FC | vs | Oakleigh Cannons FC | 4 | View |
| 07/06/22 (Tue) | 20:00 | Green Gully Reserve | 4 | Green Gully SC | vs | Whittlesea United SC | 0 | View | |
| 08/06/22 (Wed) | 19:30 | George Andrews Reserve - Pitch 1 - (NPL) | 0 | Dandenong Thunder FC | vs | Heidelberg United FC | 2 | View | |
| 14/06/22 (Tue) | 19:30 | City Vista Pavilion & Sports Field - Pitch 1 | 0 | Brimbank Stallions FC | vs | Avondale FC | 8 | View | |
| 14/06/22 (Tue) | 19:30 | Kingston Heath Soccer Complex - Pitch 1 | 3 | Bentleigh Greens SC | vs | Banyule City SC | 0 | View |
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